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KMID : 0383820150780040432
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Tuberculosis and Respiratory Diseases
2015 Volume.78 No. 4 p.432 ~ p.435
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Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium simiae: The First Reported Case in South Korea
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Jeong Suk-Hyeon
Kim Su-Young
Lee Hyun
Ham Jun-Soo
Hwang Keum-Bit
Hwang Su-Bin
Shin Sun-Hye
Chung Myung-Jin
Lee Seung-Heon
Shin Sung-Jae
Koh Won-Jung
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Abstract
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This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.
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KEYWORD
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Bronchiectasis, Mycobacterium, Nontuberculous Mycobacteria
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